Treatment of Non-vitamin K Antagonist Oral Anticoagulants: by Masaaki Uno, Kuniaki Ogasawara

By Masaaki Uno, Kuniaki Ogasawara

This ebook describes new recommendations and methods for the scientific program of non-vitamin ok antagonist oral anticoagulants (NOACs) for stroke. even though nutrition okay antagonists have routinely been used for the prevention of stroke, there are a few difficulties linked to their use, comparable to the chance of intracranial hemorrhage, the necessity for nutritional regulations, and person variability. lately, NOACs were brought as possible choices to standard anticoagulants and have gotten an alternative for treating stroke sufferers world wide. despite the fact that, their use isn't with no possibility.

Each bankruptcy describes the profitable use of NOACs for stroke sufferers and discusses their destiny effect from numerous issues of view. The publication is essentially written for neurosurgeons and neurologists yet is usually of curiosity to cardiologists excited by stroke treatment.

Show description

Read or Download Treatment of Non-vitamin K Antagonist Oral Anticoagulants: For Prevention of Stroke PDF

Similar nonfiction_14 books

De Havilland Sea Vixen

This is often the second one sequence of Warpaint. This sequence was once just like the 1st, yet incorporated color illustrations and lined a much broader diversity of airplane varieties. The sequence specializes in army airplane from the second one global warfare onwards, with an emphasis at the markings carried. each one e-book includes a concise written background of the topic lined, illustrated with color and b+w photos - including color profiles and color multi-view drawings.

Image-Based Multilevel Biomechanical Modeling for Fall-Induced Hip Fracture

Fall-induced hip fracture is a scourge overall healthiness chance between aged humans. This ebook provides an image-based multilevel modeling method of knowing the biomechanics concerned with fall-induced hip fracture. via hierarchically integrating a body-level dynamics version, a femur-level finite aspect version, and a neighborhood bone failure version, the biomechanics strategy is ready to simulate all phases in sideways falls and to include all biomechanical variables affecting hip fracture.

Singularities in Geometry, Topology, Foliations and Dynamics: A Celebration of the 60th Birthday of José Seade, Merida, Mexico, December 2014

This publication gains state of the art study on singularities in geometry, topology, foliations and dynamics and offers an outline of the present kingdom of singularity idea in those settings. Singularity conception is on the crossroad of varied branches of arithmetic and technological know-how often. in recent times there were outstanding advancements, either within the concept itself and in its family with different components.

Advances in Memristors, Memristive Devices and Systems

This e-book studies at the most recent advances in and functions of memristors, memristive units and platforms. It gathers 20 contributed chapters through topic specialists, together with pioneers within the box akin to Leon Chua (UC Berkeley, united states) and R. S. Williams (HP Labs, USA), who're really expert within the numerous issues addressed during this booklet, and covers large components of memristors and memristive units akin to: memristor emulators, oscillators, chaotic and hyperchaotic memristive platforms, keep an eye on of memristive platforms, memristor-based min-max circuits, canonic memristors, memristive-based neuromorphic functions, implementation of memristor-based chaotic oscillators, inverse memristors, linear memristor units, not on time memristive structures, flux-controlled memristive emulators, and so forth.

Additional info for Treatment of Non-vitamin K Antagonist Oral Anticoagulants: For Prevention of Stroke

Sample text

33. Hylek EM, Singer DE. Risk factors for intracranial hemorrhage in outpatients taking warfarin. Ann Intern Med. 1994;120:897–902. 34. Smith NL, Psaty BM, Furberg CD, White R, Lima JA, Newman AB, et al. Temporal trends in the use of anticoagulants among older adults with atrial fibrillation. Arch Intern Med. 1999;159:1574–8. 35. Bradley BC, Perdue KS, Tisdel KA, Gilligan DM. Frequency of anticoagulation for atrial fibrillation and reasons for its non-use at a veterans affairs medical center. Am J Cardiol.

2014;111:808–16. 3 Intracranial Bleeding 39 38. Miller MP, Trujillo TC, Nordenholz KE. Practical considerations in emergency management of bleeding in the setting of target-specific oral anticoagulants. Am J Emerg Med. 2014;32:375–82. 39. Anderson CS, Huang Y, Wang JG, Arima H, Neal B, Peng B, et al. Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT): a randomised pilot trial. Lancet Neurol. 2008;7:391–9. 40. Eerenberg ES, Kamphuisen PW, Sijpkens MK, Meijers JC, Buller HR, Levi M.

The study clearly demonstrated that both Cofact and Beriplex reversed the steady-state pharmacodynamic effects of apixaban in several coagulation assessments, including a thrombin generation assay. However, the efficacy of the four-factor PCCs on bleeding events in the subjects was not assessed. Zahir et al. evaluated the effects of edoxaban (60 mg) on bleeding following punch biopsy and reversal by a four-factor PCC (Beriplex) in a double-blind, randomized, placebo-controlled, two-way crossover study in 110 healthy subjects and found that the four-factor PCC dose-dependently reversed the effects of edoxaban, with complete reversal of bleeding duration and endogenous thrombin potential and partial reversal of PT following intravenous administration of 50 IU/kg of fourfactor PCC [42].

Download PDF sample

Rated 4.19 of 5 – based on 39 votes