Pineal Region Tumors: Diagnosis and Treatment Options by Tatsuya Kobayashi, L. Dade Lunsford

By Tatsuya Kobayashi, L. Dade Lunsford

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Extra resources for Pineal Region Tumors: Diagnosis and Treatment Options (Progress in Neurological Surgery Vol 23)

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Tsumanuma · Tanaka · Fujii 7 Tanaka R, Washiyama K: Occipital transtentorial approach to pineal region tumors. Oper Tech Neurosurg 2003;6:215–221. 8 Vaquero J, Ramiro J, Martínez R, Coca S, Bravo G: Clinicopathological experience with pineocytomas: report of five surgically treated cases. Neurosurgery 1990;27:612–619. 9 Fèvre-Montange M, Szathmari A, Champier J, Mokhtari K, Chrétien F, Coulon A, FigarellaBranger D, Polivka M, Varlet P, Uro-Coste E, Fauchon F, Jouvet A: Pineocytoma and pineal parenchymal tumors of intermediate differentiation presenting cytologic pleomorphism: a multicenter study.

16 Chiechi MV, Smirniotopoulos JG, Mena H: Pineal parenchymal tumors: CT and MR features. J Comput Assist Tomogr 1995;19:509–517. 17 Nakamura M, Saeki N, Iwadate Y, Sunami K, Osato K, Yamaura A: Neuroradiological characteristics of pineocytoma and pineoblastoma. Neuroradiology 2000;42:509–514. 18 Korogi Y, Takahashi M, Ushio Y: MRI of pineal region tumors. J Neurooncol 2001;54:251–261. 19 Provenzale JM, Weber AL, Klintworth GK, McLendon RE: Radiologic-pathologic correlation. Bilateral retinoblastoma with coexistant pinealoblastoma (trilateral retinoblastoma).

7). Proliferative Potential and Neuronal or Neurosecretory Characteristics The MIB-1 staining indices in the 4 pineocytomas, 5 PPTIMD, and 4 pineoblastomas examined are shown in table 2. The indices for the pineocytomas and PPTIMD specimens were less than 7% but those for all the pineoblastomas examined were more than 8%. The mean MIB-1 staining index of pineoblastomas was Occipital Transtentorial Approach and Combined Treatments 39 Table 2. Case representations Patient Age no. 5 ND = Not done; Rx = irradiation; Cx = chemotherapy; BLM = bleomycin; MTX = methotrexate; CBDCA = carboplatin; VP16 = etoposide; ACNU = nimustine; VBL = vinblastine; CTX = cyclophosphamide; DACT = actinomycin D; CDDP = cisplatin; L-PAM = melphalan; CR = complete response; PR = partial response; PD = progressive disease.

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