Palladium in Heterocyclic Chemistry by Li J.J., Gribble G.W.

By Li J.J., Gribble G.W.

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1 Kumada coupling Pyrrole Grignard reagents can be generated either by bromine-magnesium exchange on bromopyrroles [42-44] or by transmetalation of lithiopyrroles with magnesium bromide [45-47]. The resulting pyrrole Grignard reagents undergo a variety of coupling reactions (the Kumada coupling [48, 49]) with aryl, alkyl, and heteroaryl halides as catalyzed by palladium [42, 43, 4547]. Several examples are shown below leading to pyrroles 45--47 [43, 45, 46]. ~ PdCI2(dppb) + MgBr I THF, d, 20 h 93~ Me 46 SiMe3 i MgBr Me + /~Br PdCI2(dppb) .....

1995, 27, 129-60. 61. Campbell, I. B. in Organocopper Reagents, 1994, 217-35. : Taylor, R. J. K. Publisher: IRL Press, Oxford, UK. 62. ; Yamanaka, H. Chem. Pharm. Bull. 1988, 36, 2248-52. 63. Jeffery, T. Synthesis, 1987, 70-1. 64. ; Sinou, D. Tetrahedron Lett. 1996, 37, 5527-30. 65. 66. 67. 68. ; Ozaki, A. Bull. Chem. Soc. Jpn. 1971, 44, 581. Heck, R. ; Nolley, J. , Jr. J. Org. Chem. 1972, 37, 2320-2. ; Ohta, A. Heterocycles 1986, 24, 2093-7. ; de Meijere, A. ; 69. 70. Link, J. ; Overman, L. E.

Wolfe, J. ; Sadighi, J. ; Buchwald, S. L. J. Am. Chem. Soc. 1999, 121, 4369-78. 110. ; Morikawa, M. Tetrahedron Lett. 1965, 4387-10. 111. Tsuji, J. Acc. Chem. Res. 1969, 2, 144-52. 112. A. Godleski, in "Comprehensive Organic Synthesis" (Trost, B. ), vol. 4. 3. Pergamon, Oxford, 1991. 113. M. Moreno-Mafias, R. R. ), 1996, 66, 73-129, Academic Press. 114. ; Sinou, D. Tetrahedron Lett. 1992, 33, 2481-4. 115. Jeffery, T. J. Chem. , Chem. Commun. 1984, 1287-9. 116. Jeffery, T. Tetrahedron Lett. 1999, 40, 1673-6.

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