By E. Anne MacGregor
Thoroughly up to date and revised, this variation of Migraine in ladies explores the hyperlinks among migraine and hormonal adjustments and the powerful administration in numerous phases of lifestyles. The publication outlines the results of menstruation, being pregnant, birth control, the menopause and HRT on migraine, experiences the mechanisms concerned, and offers functional recommendation on remedy. the writer defines the categories of migraines, who will get them, and their medical prognosis. She discusses acute and prophylactic remedy and offers an outline for dealing with migraines. The publication comprises the overseas Headache Society diagnostic standards.
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Additional info for Migraine in Women
They should not be used concomitantly with ergotamine. Amitriptyline is particularly useful if there is associated depression, sleep disturbance, or tension-type headache. Higher doses are usually only necessary for associated depression. Most side-effects, including sedation, dry mouth, dizziness, and blurred vision, improve after the initial weeks of treatment. Amitriptyline is contraindicated in myocardial infarction, heart block, and closedangle glaucoma. Concomitant use of MAOIs (with or within 14 days), other antidepressives, carbamazepine, phenytoin, and alcohol should be avoided.
However, occasional use at doses found in combined analgesics is unlikely to cause harm. Ibuprofen Animal studies with ibuprofen have not shown any treatmentrelated abnormalities and the drug has been safely given during pregnancy at doses not exceeding 600 mg daily for the management of rheumatoid arthritis. Other effects are similar to those of aspirin. NSAIDs There are insufficient data to support the use of most NSAIDs in pregnant women. Paracetamol Paracetamol is the mild analgesic of choice in pregnancy provided it is not taken in combination with methionine, a drug used to prevent paracetamol toxicity.
The choice of drug usually depends on the presence of concomitant disorders. First line Beta-adrenergic blockers are particularly useful if there is associated hypertension or anxiety. Atenolol, metoprolol, nadolol, propranolol, and timolol have all shown efficacy in clinical trials although atenolol is not licensed for migraine in the UK. Typical side-effects include lethargy, vivid dreams, and cold extremities. Patients with asthma, brittle diabetes, chronic obstructive airways disease, myocardial insufficiency, and peripheral vascular disease should avoid beta-blockers.