By Peter Pollak(auth.)
Now up-to-date - the authoritative reference on some of the most interesting and hard parts of the trendy chemical industry
This hugely readable and informative reference maintains to take a finished, in-depth view of the goods, markets, and expertise of the tremendous chemical substances and company. Dr. Peter Pollak, one of many most suitable experts within the box, offers an insider's designated standpoint on advantageous chemical substances from either a technological and a advertisement perspective, protecting all fresh advancements. He offers plentiful evidence and figures together with sixty-three tables, thirty figures, and nineteen photograph inserts - making this a well-illustrated and documented text.
This reference is split into 3 parts:
Part One: The discusses the kinds of excellent chemical businesses, the diversity of goods and providers, the position of analysis and improvement, the underlying applied sciences, and the demanding situations dealing with management
Part : The enterprise explores the foremost markets for high quality chemical substances - similar to the pharmaceutical, agrochemical, and animal healthiness industries - and the suitable advertising thoughts, in addition to the bits and bobs of pricing, distribution channels, highbrow estate rights, account administration, and promotion
Part 3: Outlook examines developments reminiscent of globalization and outsourcing, forecasts destiny development and improvement by means of section, and discusses must haves for achievement within the field
This new version positive factors either up to date and new details at the offer/demand stability for effective chemical compounds and the escalating influence of rising businesses in Asia, quite from China and India. It describes the inversion of the mergers and acquisitions state of affairs from a seller's to a buyer's industry, the broadening of the fantastic chemical company version, and the increasing position of biotechnology, in addition to the impression of elevated outsourcing of chemical production and the starting to be intake of prescribed drugs and agrochemicals by way of the existence technology undefined. additionally incorporated are quite a few molecular constructions, engineering diagrams, and tables to facilitate understanding.
For an intensive realizing of the know-how, the company, and the way forward for the wonderful chemical substances undefined, this book's perception is extraordinary. it's preferrred for these within the - together with staff, providers, consumers, traders, and consulting businesses - in addition to educational and different study organisations, scholars and educators, public officers, media representatives, and somebody else who desires to comprehend the intricacies of the industry.
Fine Chemicals has been well-known as Outstanding educational identify 2012 (Choice, v.50, no. 05, January 2013).
Chapter 1 What effective chemical compounds are (pages 1–7):
Chapter 2 The fantastic Chemical (pages 8–25):
Chapter three items (pages 26–31):
Chapter four applied sciences (pages 32–48):
Chapter five amenities and crops (pages 49–65):
Chapter 6 study and improvement (pages 66–74):
Chapter 7 fee Calculation (pages 75–80):
Chapter eight administration points (pages 81–90):
Chapter nine industry dimension and constitution (pages 93–99):
Chapter 10 The company situation (pages 100–106):
Chapter eleven client Base (pages 107–140):
Chapter 12 advertising and marketing (pages 141–177):
Chapter thirteen common traits and progress Drivers (pages 179–183):
Chapter 14 Globalization (pages 184–197):
Chapter 15 Biotechnology (pages 198–202):
Chapter sixteen moral Pharmaceutical (pages 203–216):
Chapter 17 Generics (pages 217–223):
Chapter 18 different existence technological know-how Industries (pages 224–227):
Chapter 19 agreement examine enterprises (pages 228–230):
Chapter 20 end: who's Fittest for the longer term? (pages 231–235):
Read or Download Fine Chemicals: The Industry and the Business, Second Edition PDF
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Additional resources for Fine Chemicals: The Industry and the Business, Second Edition
The threshold between the two is as at about 50 amino acids. Because of their unique biological functions, a significant and growing part of new drug discovery and development is focused on this class of biomolecules. Their biological functions are determined by the exact arrangement or sequence of different amino acids in their makeup. There are 20 naturally occurring amino acids, 8 of which are defined as essential amino acids, namely l-isoleucine, l-leucine, l-lysine, l-methionine, lphenylalanine, l-valine, l-threonine, and l-tryptophan.
Several large pharmaceutical companies market fine chemicals as subsidiary activity to their production for captive use, for example, Abbott, USA; Bayer Schering Pharma, Boehringer-Ingelheim, Germany; Daiichi-Sankyo (after the takeover of Ranbaxy), Japan; Genzyme, USA; Johnson & Johnson, USA; Merck KGaA, Germany; Pfizer (formerly Upjohn), USA. The fine chemical industry is very fragmented. The top 20 companies have a market share of merely 20%, the top 40 have 30%. In comparison, the top 20 pharma companies have a market share of more than 50%.
The offerings of patient CROs, aka clinical CROs, comprise more than 30 tasks addressing the clinical part of pharmaceutical development at the interface between drugs, physicians, hospitals, and patients. 3 Tasks of “Product” Contract Research Organizations Task Description Sample Preparation Synthetic PFCs Laboratory preparation of PFCs, impurities, metabolites, etc. Product extraction, purification, and characterization Natural products Process Development General Route screening Proof of principle Sample preparation Safety and toxicology studies Analytics Process research Regulatory affairs Scale-up (kilogram-laboratory/ pilot and industrial scale plant production) Upgrading of laboratory procedures to economically and ecologically viable industrialscale manufacturing processesa (including examination of process parameters) Evaluation of the most suitable synthetic or biotechnological route (mostly by literature search) Confirmation of selected route based upon economic and quality criteria, equipment specifications, etc.