Fecal Incontinence: Diagnosis and Treatment by Adil E. Bharucha, Roberta E. Blandon, Peter J. Lunniss, S.

By Adil E. Bharucha, Roberta E. Blandon, Peter J. Lunniss, S. Mark Scott (auth.), Carlo Ratto, Giovanni B. Doglietto, Ann C. Lowry, Lars Påhlman, Giovanni Romano (eds.)

Fecal incontinence is a widespread, distressing that has a devastating effect on sufferers’ lives. despite the fact that, sufferers tend to be embarrassed and reluctant to recognize this incapacity, in order that they relinquish the opportunity of being cured and stay socially remoted. considering fecal incontinence can result from a variety of pathophysiological occasions, a correct diagnostic work-up of every sufferer is prime. at the present time, a variety of healing techniques is accessible, yet making the proper selection is pivotal to the winning administration of this situation. This booklet is aimed toward all physicians fascinated about the review and remedy of fecal incontinence. Its major goal is to study the newest advances within the epidemiologic, socio-economic, psychologic, diagnostic, and healing features of fecal incontinence, with the intention to determine instructions for powerful treatment.

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Gastroenterology 124:235–245 64. Read M, Read NW, Barber DC et al (1982) Effects of loperamide on anal sphincter function in patients complaining of chronic diarrhea with fecal incontinence and urgency. Dig Dis Sci 27:807–814 65. Cheetham MJ, Kamm MA, Phillips RK (2001) Topical phenylephrine increases anal canal resting pressure in patients with faecal incontinence. Gut 48:356–359 66. E. E. Blandon treatment of faecal incontinence. Br J Surg 87:38–42 67. Koda K, Saito N, Seike K et al (2005) Denervation of the neorectum as a potential cause of defecatory disorder following low anterior resection for rectal cancer.

Bharucha AE, Fletcher JG, Harper CM et al (2005) Relationship between symptoms and disordered continence mechanisms in women with idiopathic faecal incontinence. Gut 54:546–555 3. Andrews C, Bharucha AE, Seide B et al (2007) Rectal sensorimotor dysfunction in women with fecal incontinence. Am J Physiol Gastrointest Liver Physiol 292:G282–G289 4. Williams NS, Ogunbiyi OA, Scott SM et al (2001) Rectal augmentation and stimulated gracilis anal neosphincter: a new approach in the management of fecal urgency and incontinence.

Consequently, there remains considerable inconsistency in the literature when describing the correct neurological nomenclature of afferent neurones and pathways to the rectum. However, significant advances are being made: Drs. Bharucha and Blandon have highlighted the finding of rectal intraganglionic laminar endings (rIGLEs) in the guinea pig rectum that serve as slowly adapting mechanoreceptors [55], and other molecular mechanisms involved in mechanosensory transduction have also been identified.

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