By David J Triggle, John B Taylor
The 1st variation of complete Medicinal Chemistry was once released in 1990 and used to be rather well bought. complete Medicinal Chemistry II is far greater than an easy updating of the contents of the 1st version. thoroughly revised and accelerated, this new version has been refocused to mirror the numerous advancements and alterations during the last decade in genomics, proteomics, bioinformatics, combinatorial chemistry, high-throughput screening and pharmacology, and extra. The content material includes the main up to date, authoritative and accomplished reference textual content on modern medicinal chemistry and drug examine, overlaying significant healing sessions and goals, examine technique and organization, high-throughput applied sciences, computer-assisted layout, ADME and chosen case histories. it's this insurance of the method, applied sciences, rules and purposes of medicinal chemistry in one paintings that may make finished Medicinal Chemistry II a different paintings of reference and a unmarried aspect of access to the literature for pharmaceutical and biotechnology scientists of all disciplines and for lots of executives as well.Also on hand on-line through ScienceDirect (2006) - that includes huge looking, looking out, and inner cross-referencing among articles within the paintings, plus dynamic linking to magazine articles and summary databases, making navigation versatile and straightforward. for additional info, pricing thoughts and availability stopover at www.info.sciencedirect.com. * Comprehensively reports - the concepts, applied sciences, rules and purposes of recent medicinal chemistry * offers an international and present point of view of modern drug discovery method and discusses the key healing periods and objectives* encompasses a particular choice of case stories and private assays reviewing the invention and improvement of key medications
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Additional info for Comprehensive Medicinal Chemistry II, Volume 4 : Computer-Assisted Drug Design
Med. Chem. 1996, 39, 1571–1574. ; Meadows, R. ; Harlan, J. ; Yoon, H. ; Shuker, S. ; Chang, B. ; Minn, A. J. et al. Science 1997, 275, 983–986. Chin, J. ; Schepartz, A. Angew. Chem. Int. Ed. Engl. 2001, 40, 3806–3809, 3922–2925. Ernst, J. ; Park, H. ; Hamilton, A. D. Angew. Chem. Int. Ed. Engl. 2003, 42, 535–539. Ernst, J. ; Debnath, A. ; Hamilton, A. D. Angew. Chem. Int. Ed. Engl. 2002, 41, 278–281. Marshall, G. ; Bosshard, H. E. Circul. Res. 1972, 31, 143–150. ; Smith, G. ; Balasubramanian, T.
Chalmers, D. ; Marshall, G. R. J. Am. Chem. Soc. 1995, 117, 5927–5937. ; Marshall, G. R. J. Am. Chem. Soc. 1998, 120, 5363–5372. Hodgkin, E. ; Clark, J. ; Miller, K. ; Marshall, G. R. Biopolymers 1990, 30, 533–546. Smith, A. ; Favor, D. ; Sprengeler, P. ; Guzman, M. ; Carroll, P. ; Furst, G. ; Hirschmann, R. Bioorg. Med. Chem. 1999, 7, 9–22. Jacoby, E. Bioorg. Med. Chem. Lett. 2002, 12, 891–893. ; Park, H. ; Ernst, J. ; Orner, B. ; Hamilton, A. D. J. Am. Chem. Soc. 2002, 124, 11838–11839. Orner, B.
Soc. 2003, 125, 8151–8162. 39 40 Introduction to Computer-Assisted Drug Design – Overview and Perspective for the Future 244. ; Czarnik, A. , DeWitt, S. ; American Chemical Society: Washington, DC, 1997. 245. Wiley, R. ; Rich, D. H. Med. Res. Rev. 1993, 13, 327–384. 246. Evans, B. ; Rittle, K. ; Bock, M. ; DiPardo, R. ; Freidinger, R. ; Whitter, W. ; Lundell, G. ; Veber, D. ; Anderson, P. ; Chang, R. S. et al. J. Med. Chem. 1988, 31, 2235–2246. 247. Patchett, A. ; Nargund, R. P. Annu. Rep. Med.