By Sudha R. Kini MD
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Germinal center cells of lymphoid tissue). D: Biphasic. , fibroadenoma). Note an epithelial component (E), widely separated by neoplastic stromal component (S) (H&E). E: Biphasic. FNA of a fibroadenoma showing epithelial tissue fragments in the background of abundant stroma. F: Triphasic. , Wilms’ tumor). Histologic section showing a glandular and a primitive cell component (H&E). , germinal center cells of the lymphoid follicle or hematopoietic cells from a bone marrow) (Figs. 4A to C). The term monophasic, biphasic, or triphasic relate to the number of cell lines presenting different morphologic patterns in a given neoplasm.
Intermediate filaments rhabdoid tumors). 21 22 Chapter 1: Overview remember that no matter how extreme or bizarre cytoplasmic features appear, they cannot differentiate malignant from benign. Stroma The term stroma describes the supporting tissue or matrix of an organ, in contrast to functioning tissue or the paren- chyma. The supporting tissue presents several characteristics, which are, at times, unique to a lesion. It can be a loose myxoid with abundant ground substance, collagenized, fi brillar, chondroid, osteoid, or could contain amyloid (Fig.
Transmitted disease and thereby decreasing the incidence of cervical epithelial neoplasia. The vaccine therapy is still in the preliminary stages and long-term follow-up studies are necessary to judge the effects of the vaccine. All the above events contributed immensely to lowering the incidence of cervical cancer and related deaths in the Western world. However, the success of the tremendously useful test was overshadowed by some instances of missed diagnoses of cervical cancers and the publicity it received in media.