By Johanna L'age-Stehr
International experts in Microbiology, Infectious ailments, inner medication, Cardiology Immunology, Pneumonolgy, Neurology and Epidemiology amassed to this workshop to debate and increase interdisciplinary wisdom at the attainable etiological position of Chlamydia pneumoniae, a common human breathing an infection, within the pathogenesis of power inflammatory illnesses with significant public health and wellbeing effect akin to: - atherosclerosis, - heart problems, - grownup onset bronchial asthma bronchiale, - power obstructive pulmonary diseases,- reactive arthritis,- Morbus Alzheimer and - a number of Sclerosis. present deficits and targets in standardisation of diagnostic instruments, simple and utilized examine, layout of epidemiological and tracking of remedy reviews have been pointed out. a distinct characteristic of this publication is the great selection of state-of-the-art evaluation articles within the a variety of fields with many references and the enclosure of the controverse discussions to every article which supplies the reader with a lifely photograph at the function of Chlamydia pneumoniae in persistent diseases.
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Additional resources for Chlamydia pneumoniae and Chronic Diseases: Proceedings of the State-of-the-Art Workshop held at the Robert Koch-Institut Berlin on 19 and 20 March 1999
On Reference Immunofluorescence 79% USA (23) Immunohistochemistry USA (11) Immunohistochemistry 39% 45% 42% Japan South Africa (26) (13) Immunohistochemistry 45% USA Culture 8% 0% 16 % 17% USA Germany (4) (27) (33) (16) Immunohistochemistry Culture Culture PCR USA USA (11) Japan South Africa USA USA Germany (26) PCR PCR PCR 55% 43 % 32 % 2% 26% Aortic valve PCR 49% Sweden (24) Carotid artery Immunohistochemistry 57% 55% 6% 15 % USA (7) (35) (9) (21) PCR peR Immunohistochemistry Culture PCR Aorta Immunohistochemistry PCR 33 % 18 % 44% PCR 51 % Immunohistochemistry PCR 40 % 55 % 30 % 15 % PCR A.
Ossewaarde: We have learned from Dr. Byrne that Hsp60 and Chlamydia LPS might playa very important role in atherogenesis in animal models. You showed recent studies in which C. pneumoniae and the mouse pneumonitis strain were used to infect animals, and C. pneumoniae enhances atherosclerosis but mouse pneumonitis does not. And mouse pneumonitis also has Hsp60 and Chlamydial LPS. Could someone comment on these results? Leinonen: As I said, C. pneumoniae may have some extra features which contribute to the pathogenesis.
Proc Nat! Acad Sci USA 92: 6911-6914 12. Kuo CC, Jackson LA, Campbell LA, Grayston IT (1995) Chlamydia pneumoniae (TWAR). Clin Microbiol Rev 8: 451-461 13. Kuo CC, Shor A, Campbell LA, Fukushi H, Patton DL, Grayston JT (1993) Demonstration of Chlamydia pneumoniae in atherosclerotic lesions of coronary arteries. J Infect Dis 167: 841-849 14. Libby P (1996) Atheroma: more than mush. Lancet 348 (suppl I): s4-s7 15. Maass M (1996) Chlamydia pneumoniae in der Atiologie respiratorischer und vaskuliirer Erkrankungen des Menschen.